Convenient triple parasite protection. Trifexis® (spinosad + milbemycin oxime) is the monthly, beef-flavored tablet that kills fleas and prevents flea infestations, prevents heartworm disease, and treats and controls hookworm, roundworm and whipworm infections. This powerful protection is approved for use in dogs and puppies 8 weeks of age or older and 5 pounds of body weight or greater.
Why choose Trifexis® for your dog or puppy?
Kills fleas and prevents infestations
Treats and controls hookworm, roundworm and whipworm infections.
Prevents heartworm disease
Trifexis® kills the juvenile heartworms before they can grow and reproduce.
Monthly and easy administration
Beef-flavored tablet for easy, oral delivery.
Trusted by vets for more than 25 years.
Compare Trifexis® to other brands.
Compare Trifexis®, Heartgard® Plus, Nexgard® and Bravecto™.
Fleas & Infestation
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Protecting your dog from parasites is easy. Once a month, every month.
Triple parasite protection
Protect all month long with just one tablet
Starts killing fleas in 30 minutes.
How quickly does Trifexis start to work?
How long does Trifexis last?
What types of parasites does Trifexis kill?
My dog has tapeworms. Will Trifexis get rid of those?
How often does my dog need to take Trifexis?
How should I give Trifexis to my dog?
The package reads “chewable.” What if my dog swallows the tablet whole?
Spinosad and Milbemycin oxime
The use of ivermectin at higher than FDA approved doses at the same time as Trifexis can result in serious side effects. Treatment with fewer than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. Use with caution in breeding females. The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy. The most common adverse reactions reported are vomiting, decreased activity, itching, decreased appetite, and diarrhea. To ensure heartworm prevention, observe your dog for one hour after administration. If vomiting occurs within an hour of administration, re-dose with another full dose. Puppies less than 14 weeks of age may experience a higher rate of vomiting. For complete safety information, please see Trifexis product label or ask your veterinarian.
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